A man leaves his father and mother and is united to his wife, and they become one flesh.
Genesis 2:24

Words: William C. Doane, 1880. Appeared in The Church Hymnary, edited by Edwin A. Bedell (New York: Charles E. Merrill, 1891), number 911.
Music: Isca (Wood) Daniel J. Wood, in The Church Hymnal, edited by Charles L. Hutchins (Boston, Massachusetts: The Parish Choir, 1898), number 239 (🔊 pdf nwc).
If you know where to get a good photo of Wood (head & shoulders, at least 200×300 pixels),
To Thee, O Father, throned on high
Our marriage hymn we duly sing;
Knit Thou the sacred bond we tie,
And do Thou bless the wedding ring.
Thy love, at first, in Paradise,
It was that made one flesh of twin;
Work Thou, while here our prayers arise,
That sacred mystery again.
To Thee, O Jesus, throned beside
Thy Father’s right hand, here we cry;
True Bridegroom of Thy spotless bride,
With all Thy human love, draw nigh.
Our human nature, Thy divine
Has wedded, and in Thee, dear Lord,
As Cana’s water turned to wine,
Its lost godlikeness is restored.
O Holy Ghost, the Paraclete,
Thee too we worship, God and Lord,
And honor Thee, with praises meet,
One with the Father and the Word,
Lord and Life-giver, hear our prayer,
Come, sanctify and bless, and guide,
Strengthen, and shelter ’neath Thy care,
The life of bridegroom and bride.
O God triune, whom Heaven’s host
Adores, with sweet and ceaseless song;
O Father, Son and Holy Ghost,
To whom all worship doth belong;
Hear, in these echoes faint and dim,
Of chant and prayer and holy psalm,
Their songs, the heavenly feast who hymn,
The marriage supper of the Lamb.