Born: February 22, 1819, Cambridge, Massachusetts.
Died: August 12, 1891, Cambridge, Massachusetts.
Buried: Mount Auburn Cemetery, Cambridge, Massachusetts.
James was the son of Charles Lowell and Harriette Bracket Spence. He married twice, to Maria White (1844) and Frances Dunlap (1857).
A prominent poet and author, he graduated from Harvard College in 1838, and was admitted to the bar in 1840.
He became a Professor of Modern Languages and Literature at Harvard in 1855, succeeding Henry Wadsworth Longfellow.
He edited the Atlantic Monthly (1857–62) and the North American Review (1863–72). He also served as American minister to Spain (1877–80) and ambassador to England (1880–85).